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Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target

The Coenzyme A (CoA), as a cofactor involved in >100 metabolic reactions, is essential to the basic biochemistry of life. Here, we investigated the CoA biosynthetic pathway of Entamoeba histolytica (E. histolytica), an enteric protozoan parasite responsible for human amebiasis. We identified four...

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Detalles Bibliográficos
Autores principales:	Nurkanto, Arif, Jeelani, Ghulam, Yamamoto, Takehiro, Naito, Yoshiko, Hishiki, Takako, Mori, Mihoko, Suematsu, Makoto, Shiomi, Kazuro, Hashimoto, Tetsuo, Nozaki, Tomoyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114107/ https://www.ncbi.nlm.nih.gov/pubmed/29518650 http://dx.doi.org/10.1016/j.ijpddr.2018.02.004

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