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Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13

Haemonchus contortus, one of the most economically important parasites of small ruminants, has become resistant to the anthelmintic ivermectin. Deciphering the role of P-glycoproteins in ivermectin resistance is desirable for understanding and overcoming this resistance. In the model nematode, Caeno...

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Detalles Bibliográficos
Autores principales: David, Marion, Lebrun, Chantal, Duguet, Thomas, Talmont, Franck, Beech, Robin, Orlowski, Stéphane, André, François, Prichard, Roger K., Lespine, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114108/
https://www.ncbi.nlm.nih.gov/pubmed/29571165
http://dx.doi.org/10.1016/j.ijpddr.2018.02.001