Normal saline for intravenous fluid therapy in critically ill patients

The efficacy and safety of normal saline (NS) for fluid therapy in critically ill patients remain controversy. In this review, we summarized the evidence of randomized controlled trials (RCTs) which compared NS with other solutions in critically ill patients. The results showed that when compared wi...

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Detalles Bibliográficos
Autores principales: Zhou, Fei-Hu, Liu, Chao, Mao, Zhi, Ma, Peng-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114124/
https://www.ncbi.nlm.nih.gov/pubmed/29429774
http://dx.doi.org/10.1016/j.cjtee.2017.04.012
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author Zhou, Fei-Hu
Liu, Chao
Mao, Zhi
Ma, Peng-Lin
author_facet Zhou, Fei-Hu
Liu, Chao
Mao, Zhi
Ma, Peng-Lin
author_sort Zhou, Fei-Hu
collection PubMed
description The efficacy and safety of normal saline (NS) for fluid therapy in critically ill patients remain controversy. In this review, we summarized the evidence of randomized controlled trials (RCTs) which compared NS with other solutions in critically ill patients. The results showed that when compared with 6% hydroxyethyl starch (HES), NS may reduce the onset of acute kidney injury (AKI). However, there is no significant different in mortality and incidence of AKI when compared with 10% HES, albumin and buffered crystalloid solution. Therefore, it is important to prescribe intravenous fluid for patients according to their individual condition.
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spelling pubmed-61141242018-08-31 Normal saline for intravenous fluid therapy in critically ill patients Zhou, Fei-Hu Liu, Chao Mao, Zhi Ma, Peng-Lin Chin J Traumatol Review Article The efficacy and safety of normal saline (NS) for fluid therapy in critically ill patients remain controversy. In this review, we summarized the evidence of randomized controlled trials (RCTs) which compared NS with other solutions in critically ill patients. The results showed that when compared with 6% hydroxyethyl starch (HES), NS may reduce the onset of acute kidney injury (AKI). However, there is no significant different in mortality and incidence of AKI when compared with 10% HES, albumin and buffered crystalloid solution. Therefore, it is important to prescribe intravenous fluid for patients according to their individual condition. Elsevier 2018-02 2018-01-31 /pmc/articles/PMC6114124/ /pubmed/29429774 http://dx.doi.org/10.1016/j.cjtee.2017.04.012 Text en © 2018 Production and hosting by Elsevier B.V. on behalf of Daping Hospital and the Research Institute of Surgery of the Third Military Medical University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Zhou, Fei-Hu
Liu, Chao
Mao, Zhi
Ma, Peng-Lin
Normal saline for intravenous fluid therapy in critically ill patients
title Normal saline for intravenous fluid therapy in critically ill patients
title_full Normal saline for intravenous fluid therapy in critically ill patients
title_fullStr Normal saline for intravenous fluid therapy in critically ill patients
title_full_unstemmed Normal saline for intravenous fluid therapy in critically ill patients
title_short Normal saline for intravenous fluid therapy in critically ill patients
title_sort normal saline for intravenous fluid therapy in critically ill patients
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114124/
https://www.ncbi.nlm.nih.gov/pubmed/29429774
http://dx.doi.org/10.1016/j.cjtee.2017.04.012
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