Syntheses of Highly Functionalized Spirocyclohexenes by Formal [4+2] Annulation of Arylidene Azlactones with Allenoates

A straightforward phosphine‐catalyzed formal [4+2] annulation between α‐branched allenoates and arylidene azlactones has been developed to access highly functionalized spirocyclohexenes. This cyclization favors the γ‐addition of the phosphine‐activated allenoates over a β′‐addition pathway. Detailed...

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Detalles Bibliográficos
Autores principales: Eitzinger, Andreas, Zielke, Katharina, Widhalm, Michael, Robiette, Raphaël, Waser, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114148/
https://www.ncbi.nlm.nih.gov/pubmed/30175031
http://dx.doi.org/10.1002/ajoc.201800275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114148/
https://www.ncbi.nlm.nih.gov/pubmed/30175031
http://dx.doi.org/10.1002/ajoc.201800275

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