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SP1-induced lncRNA AGAP2-AS1 expression promotes chemoresistance of breast cancer by epigenetic regulation of MyD88

BACKGROUND: Resistance to trastuzumab has become a leading cause of mortality in breast cancer patients and is one of the major obstacles for improving the clinical outcome. Cell behavior can be modulated by long non-coding RNAs (lncRNAs), but the contribution of lncRNAs in trastuzumab resistance to...

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Detalles Bibliográficos
Autores principales: Dong, Huaying, Wang, Wei, Mo, Shaowei, Chen, Ru, Zou, Kejian, Han, Jing, Zhang, Fan, Hu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114182/
https://www.ncbi.nlm.nih.gov/pubmed/30157918
http://dx.doi.org/10.1186/s13046-018-0875-3

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