BRAF and AXL oncogenes drive RIPK3 expression loss in cancer

Necroptosis is a lytic programmed cell death mediated by the RIPK1-RIPK3-MLKL pathway. The loss of Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) expression and necroptotic potential have been previously reported in several cancer cell lines; however, the extent of this loss across c...

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Detalles Bibliográficos
Autores principales: Najafov, Ayaz, Zervantonakis, Ioannis K., Mookhtiar, Adnan K., Greninger, Patricia, March, Ryan J., Egan, Regina K., Luu, Hoang Son, Stover, Daniel G., Matulonis, Ursula A., Benes, Cyril H., Yuan, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114281/
https://www.ncbi.nlm.nih.gov/pubmed/30157175
http://dx.doi.org/10.1371/journal.pbio.2005756

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