Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia

BACKGROUND: The bone marrow microenvironment constitutes a sanctuary for leukemia cells. Recent evidence indicates that environment-mediated drug resistance arises from a reciprocal influence between tumor cells and the surrounding stroma. The present study aimed to investigate the effect of chronic...

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Detalles Bibliográficos
Autores principales: Ding, Lu, Zhang, Wan, Yang, Lili, Pelicano, Helene, Zhou, Kaiwen, Yin, Ran, Huang, Ruibin, Zeng, Junyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114474/
https://www.ncbi.nlm.nih.gov/pubmed/30210236
http://dx.doi.org/10.2147/OTT.S170392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114474/
https://www.ncbi.nlm.nih.gov/pubmed/30210236
http://dx.doi.org/10.2147/OTT.S170392

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