The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins

The N-end rule pathway is a proteolytic system in which single N-terminal amino acids of proteins act as a class of degrons (N-degrons) that determine the half-lives of proteins. We have previously identified a family of mammals N-recognins (termed UBR1, UBR2, UBR4/p600, and UBR5/EDD) whose conserve...

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Detalles Bibliográficos
Autores principales: Kim, Sung Tae, Lee, Yoon Jee, Tasaki, Takafumi, Hwang, Joonsung, Kang, Min Jueng, Yi, Eugene C., Kim, Bo Yeon, Kwon, Yong Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114712/
https://www.ncbi.nlm.nih.gov/pubmed/30157281
http://dx.doi.org/10.1371/journal.pone.0202260

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