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Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases

Exposure to vinclozolin has been shown to induce the epigenetic transgenerational inheritance of increased susceptibility to disease, and to induce transgenerational changes to the epigenome. In the current study, gestating F0 generation rats were exposed to vinclozolin, and the subsequent F1, F2 an...

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Detalles Bibliográficos
Autores principales: Nilsson, Eric, King, Stephanie E., McBirney, Margaux, Kubsad, Deepika, Pappalardo, Michelle, Beck, Daniel, Sadler-Riggleman, Ingrid, Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114855/
https://www.ncbi.nlm.nih.gov/pubmed/30157260
http://dx.doi.org/10.1371/journal.pone.0202662