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Sfrp1 attenuates TAC-induced cardiac dysfunction by inhibiting Wnt signaling pathway- mediated myocardial apoptosis in mice

BACKGROUND: Hemodynamic overload causes cardiac hypertrophy leading to heart failure. Wnt signaling pathway was reported activated in heart failure. Secreted frizzled related protein 1 (Sfrp1) is a suppressor of Wnt signaling activation. The aim of the present study was to investigate the protective...

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Detalles Bibliográficos
Autores principales:	Pan, Shuo, Zhao, Xiujuan, Wang, Xu, Tian, Xin, Wang, Yuanbo, Fan, Rong, Feng, Na, Zhang, Shumiao, Gu, Xiaoming, Jia, Min, Li, Juan, Yang, Lu, Wang, Kaiyan, Guo, Haitao, Pei, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114876/ https://www.ncbi.nlm.nih.gov/pubmed/30153824 http://dx.doi.org/10.1186/s12944-018-0832-3

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