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Fungicidal action of geraniol against Candida albicans is potentiated by abrogated CaCdr1p drug efflux and fluconazole synergism

Among the several mechanisms of multidrug resistance (MDR), overexpression of drug efflux pumps CaCdr1p and CaMdr1p belonging to ATP binding cassette (ABC) and major facilitator superfamily (MFS) respectively remain the predominant mechanisms of candidal infections. Therefore inhibiting or modulatin...

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Detalles Bibliográficos
Autores principales: Singh, Shweta, Fatima, Zeeshan, Ahmad, Kamal, Hameed, Saif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114893/
https://www.ncbi.nlm.nih.gov/pubmed/30157240
http://dx.doi.org/10.1371/journal.pone.0203079