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Fungicidal action of geraniol against Candida albicans is potentiated by abrogated CaCdr1p drug efflux and fluconazole synergism
Among the several mechanisms of multidrug resistance (MDR), overexpression of drug efflux pumps CaCdr1p and CaMdr1p belonging to ATP binding cassette (ABC) and major facilitator superfamily (MFS) respectively remain the predominant mechanisms of candidal infections. Therefore inhibiting or modulatin...
Autores principales: | Singh, Shweta, Fatima, Zeeshan, Ahmad, Kamal, Hameed, Saif |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114893/ https://www.ncbi.nlm.nih.gov/pubmed/30157240 http://dx.doi.org/10.1371/journal.pone.0203079 |
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