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ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization
We present ggsashimi, a command-line tool for the visualization of splicing events across multiple samples. Given a specified genomic region, ggsashimi creates sashimi plots for individual RNA-seq experiments as well as aggregated plots for groups of experiments, a feature unique to this software. C...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114895/ https://www.ncbi.nlm.nih.gov/pubmed/30118475 http://dx.doi.org/10.1371/journal.pcbi.1006360 |
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author | Garrido-Martín, Diego Palumbo, Emilio Guigó, Roderic Breschi, Alessandra |
author_facet | Garrido-Martín, Diego Palumbo, Emilio Guigó, Roderic Breschi, Alessandra |
author_sort | Garrido-Martín, Diego |
collection | PubMed |
description | We present ggsashimi, a command-line tool for the visualization of splicing events across multiple samples. Given a specified genomic region, ggsashimi creates sashimi plots for individual RNA-seq experiments as well as aggregated plots for groups of experiments, a feature unique to this software. Compared to the existing versions of programs generating sashimi plots, it uses popular bioinformatics file formats, it is annotation-independent, and allows the visualization of splicing events even for large genomic regions by scaling down the genomic segments between splice sites. ggsashimi is freely available at https://github.com/guigolab/ggsashimi. It is implemented in python, and internally generates R code for plotting. |
format | Online Article Text |
id | pubmed-6114895 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-61148952018-09-15 ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization Garrido-Martín, Diego Palumbo, Emilio Guigó, Roderic Breschi, Alessandra PLoS Comput Biol Research Article We present ggsashimi, a command-line tool for the visualization of splicing events across multiple samples. Given a specified genomic region, ggsashimi creates sashimi plots for individual RNA-seq experiments as well as aggregated plots for groups of experiments, a feature unique to this software. Compared to the existing versions of programs generating sashimi plots, it uses popular bioinformatics file formats, it is annotation-independent, and allows the visualization of splicing events even for large genomic regions by scaling down the genomic segments between splice sites. ggsashimi is freely available at https://github.com/guigolab/ggsashimi. It is implemented in python, and internally generates R code for plotting. Public Library of Science 2018-08-17 /pmc/articles/PMC6114895/ /pubmed/30118475 http://dx.doi.org/10.1371/journal.pcbi.1006360 Text en © 2018 Garrido-Martín et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Garrido-Martín, Diego Palumbo, Emilio Guigó, Roderic Breschi, Alessandra ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization |
title | ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization |
title_full | ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization |
title_fullStr | ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization |
title_full_unstemmed | ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization |
title_short | ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization |
title_sort | ggsashimi: sashimi plot revised for browser- and annotation-independent splicing visualization |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114895/ https://www.ncbi.nlm.nih.gov/pubmed/30118475 http://dx.doi.org/10.1371/journal.pcbi.1006360 |
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