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Somatic genome alterations in relation to age in lung squamous cell carcinoma

Lung squamous cell carcinoma (LUSC) is the most common cause of global cancer-related mortality and the major risk factors is smoking consumption. By analyzing ∼500 LUSC samples from The Cancer Genome Atlas, we detected a higher mutational burden as well as a higher level of methylation changes in y...

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Detalles Bibliográficos
Autores principales: Meucci, Stefano, Keilholz, Ulrich, Heim, Daniel, Klauschen, Frederick, Cacciatore, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114948/
https://www.ncbi.nlm.nih.gov/pubmed/30181806
http://dx.doi.org/10.18632/oncotarget.25848

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