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Somatic genome alterations in relation to age in lung squamous cell carcinoma
Lung squamous cell carcinoma (LUSC) is the most common cause of global cancer-related mortality and the major risk factors is smoking consumption. By analyzing ∼500 LUSC samples from The Cancer Genome Atlas, we detected a higher mutational burden as well as a higher level of methylation changes in y...
Autores principales: | Meucci, Stefano, Keilholz, Ulrich, Heim, Daniel, Klauschen, Frederick, Cacciatore, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114948/ https://www.ncbi.nlm.nih.gov/pubmed/30181806 http://dx.doi.org/10.18632/oncotarget.25848 |
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