Cargando…

Accelerated BRAF mutation analysis using a fully automated PCR platform improves the management of patients with metastatic melanoma

BACKGROUND: Determination of BRAF status is important for the therapeutic management of patients with metastatic melanoma. OBJECTIVES: We evaluated the impact of a faster determination of BRAF mutational status on the delay between initial consultation and initiation of treatment. RESULTS: For the F...

Descripción completa

Detalles Bibliográficos
Autores principales:	Serre, Delphine, Salleron, Julia, Husson, Marie, Leroux, Agnès, Gilson, Pauline, Merlin, Jean-Louis, Geoffrois, Lionnel, Harlé, Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114952/ https://www.ncbi.nlm.nih.gov/pubmed/30181812 http://dx.doi.org/10.18632/oncotarget.25957

Ejemplares similares

Detection of BRAF Mutations Using a Fully Automated Platform and Comparison with High Resolution Melting, Real-Time Allele Specific Amplification, Immunohistochemistry and Next Generation Sequencing Assays, for Patients with Metastatic Melanoma
por: Harlé, Alexandre, et al.
Publicado: (2016)

Integrated routine workflow using next-generation sequencing and a fully-automated platform for the detection of KRAS, NRAS and BRAF mutations in formalin-fixed paraffin embedded samples with poor DNA quality in patients with colorectal carcinoma
por: Franczak, Claire, et al.
Publicado: (2019)

Evaluation of KRAS, NRAS and BRAF hotspot mutations detection for patients with metastatic colorectal cancer using direct DNA pipetting in a fully-automated platform and Next-Generation Sequencing for laboratory workflow optimisation
por: Gilson, Pauline, et al.
Publicado: (2019)

Evaluation of 3 molecular-based assays for microsatellite instability detection in formalin-fixed tissues of patients with endometrial and colorectal cancers
por: Gilson, Pauline, et al.
Publicado: (2020)

Evaluation and validation of HPV real-time PCR assay for the detection of HPV DNA in oral cytobrush and FFPE samples
por: Harlé, Alexandre, et al.
Publicado: (2018)

Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers
por: Gilson, Pauline, et al.
Publicado: (2021)

Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer
por: Franczak, Claire, et al.
Publicado: (2020)

Personalized follow-up of circulating DNA in resected stage III/IV melanoma: PERCIMEL multicentric prospective study protocol
por: Geoffrois, Lionnel, et al.
Publicado: (2023)

Uncommon mutational profiles of metastatic colorectal cancer detected during routine genotyping using next generation sequencing
por: Franczak, Claire, et al.
Publicado: (2019)

Prospective evaluation of two screening methods for molecular testing of metastatic melanoma: Diagnostic performance of BRAF V600E immunohistochemistry and of a NRAS-BRAF fully automated real-time PCR-based assay
por: Vallée, Audrey, et al.
Publicado: (2019)

Optimization of routine KRAS mutation PCR-based testing procedure for rational individualized first-line-targeted therapy selection in metastatic colorectal cancer
por: Chretien, Anne-Sophie, et al.
Publicado: (2013)

Detection of Microsatellite Instability: State of the Art and Future Applications in Circulating Tumour DNA (ctDNA)
por: Gilson, Pauline, et al.
Publicado: (2021)

Deciphering Tumour Heterogeneity: From Tissue to Liquid Biopsy
por: Gilson, Pauline, et al.
Publicado: (2022)

Rapid BRAF mutation tests in patients with advanced melanoma: comparison of immunohistochemistry, Droplet Digital PCR, and the Idylla Mutation Platform
por: Bisschop, Cornelis, et al.
Publicado: (2018)

CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines
por: Witz, Andréa, et al.
Publicado: (2023)

Factors associated with under-reporting of head and neck squamous cell carcinoma in cause-of-death records: A comparative study of two national databases in France from 2008 to 2012
por: Even, Caroline, et al.
Publicado: (2021)

Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen(®) FFPE BRAF qPCR assay
por: Sørensen, Anna Lahn, et al.
Publicado: (2023)

Somatic substitution signature as an innovative tool in lung cancer diagnosis
por: Busca, Stéphane, et al.
Publicado: (2019)

Towards a fully automated algorithm driven platform for biosystems design
por: HamediRad, Mohammad, et al.
Publicado: (2019)

LB1578. Fully Automated Real-Time PCR for Detection of Candida auris
por: Jiang, Alice, et al.
Publicado: (2022)

SMAD4 and the TGFβ Pathway in Patients with Pancreatic Ductal Adenocarcinoma
por: Dardare, Julie, et al.
Publicado: (2020)

Improvement of the quality of BRAF testing in melanomas with nationwide external quality assessment, for the BRAF EQA group
por: Emile, Jean-François, et al.
Publicado: (2013)

Implementation and Evaluation of a Fully Automated Multiplex Real-Time PCR Assay on the BD Max Platform to Detect and Differentiate Herpesviridae from Cerebrospinal Fluids
por: Köller, Thomas, et al.
Publicado: (2016)

Development of a Rapid and Fully Automated Multiplex Real-Time PCR Assay for Identification and Differentiation of Vibrio cholerae and Vibrio parahaemolyticus on the BD MAX Platform
por: Li, Zhenpeng, et al.
Publicado: (2021)

Assessment of the Concordance and Diagnostic Accuracy Between Elecsys and Lumipulse Fully Automated Platforms and Innotest
por: Dakterzada, Farida, et al.
Publicado: (2021)

Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma
por: Spagnolo, Francesco, et al.
Publicado: (2014)

Targeting BRAF for patients with melanoma
por: Arkenau, H-T, et al.
Publicado: (2011)

Emerging Roles of DDB2 in Cancer
por: Gilson, Pauline, et al.
Publicado: (2019)

Fully automated real-time PCR for EGFR testing in non-small cell lung carcinoma
por: Colling, Richard, et al.
Publicado: (2018)

ZAF, the first open source fully automated feeder for aquatic facilities
por: Lange, Merlin, et al.
Publicado: (2021)

VIDAS-EDRA fully automated testing of autoantibodies to citrullinated proteins for the diagnosis of rheumatoid arthritis
por: Nogueira, L, et al.
Publicado: (2004)

A Fully Automated Continuous‐Flow Platform for Fluorescence Quenching Studies and Stern–Volmer Analysis
por: Kuijpers, Koen P. L., et al.
Publicado: (2018)

Pneumatically Driven Microfluidic Platform and Fully Automated Particle Concentration System for the Capture and Enrichment of Pathogens
por: Choi, Hong Jin, et al.
Publicado: (2023)

DataPype: A Fully Automated Unified Software Platform for Computer-Aided Drug Design
por: Khan, Mohemmed Faraz, et al.
Publicado: (2023)

FireProt 2.0: web-based platform for the fully automated design of thermostable proteins
por: Musil, Milos, et al.
Publicado: (2023)

Expression of pEGFR and pAKT as response-predictive biomarkers for RAS wild-type patients to anti-EGFR monoclonal antibodies in metastatic colorectal cancers
por: Harlé, A, et al.
Publicado: (2015)

Dual Epigenetic Regulation of ERα36 Expression in Breast Cancer Cells
por: Thiebaut, Charlène, et al.
Publicado: (2019)

BET and BRAF inhibitors act synergistically against BRAF‐mutant melanoma
por: Paoluzzi, Luca, et al.
Publicado: (2016)

Inhibition of BRAF and BRAF+MEK drives a metastatic switch in melanoma
por: Smalley, Keiran SM, et al.
Publicado: (2015)

A Point-of-Care Device for Fully Automated, Fast and Sensitive Protein Quantification via qPCR
por: Cavallo, Francesca Romana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lv6b3ndodrdkc7q088geumb2ir