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Paradoxical counteraction by imatinib against cell death in myeloid progenitor 32D cells expressing p210BCR-ABL

Chronic myeloid leukemia (CML) is believed to be caused by the tyrosine kinase p210BCR-ABL, which exhibits growth-promoting and anti-apoptotic activities. However, mechanisms that allow cell differentiation in CML still remain elusive. Here we established tetracycline (Tet)-regulatable p210BCR-ABL-e...

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Detalles Bibliográficos
Autores principales:	Takita, Morichika, Tsukahara, Fujiko, Mishima, Taishi, Ieguchi, Katsuaki, Yamada, Masayuki, Honda, Hiroaki, Maru, Yoshiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114964/ https://www.ncbi.nlm.nih.gov/pubmed/30167087 http://dx.doi.org/10.18632/oncotarget.25849

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