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Suppression of SOCS3 enhances TRAIL-induced cell growth inhibition through the upregulation of DR4 expression in renal cell carcinoma cells

BACKGROUND: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a tumor-selective apoptosis inducer that is expressed in natural killer cells, whose cytotoxicity is activated by interferon (IFN). We investigated the effect of suppressor of cytokine signaling (SOCS) 3 on the expression...

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Detalles Bibliográficos
Autores principales:	Yabe, Michihiro, Ishibashi, Kei, Onagi, Akifumi, Tanji, Ryo, Honda-Takinami, Ruriko, Koguchi, Tomoyuki, Matsuoka, Kanako, Hoshi, Seiji, Hata, Junya, Kataoka, Masao, Ogawa, Soichiro, Hiraki, Hiroyuki, Haga, Nobuhiro, Kojima, Yoshiyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114968/ https://www.ncbi.nlm.nih.gov/pubmed/30167088 http://dx.doi.org/10.18632/oncotarget.25851

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