Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays

Poxvirus adaptation can involve combinations of recombination-driven gene copy number variation and beneficial single nucleotide variants (SNVs) at the same loci. How these distinct mechanisms of genetic diversification might simultaneously facilitate adaptation to host immune defenses is unknown. W...

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Detalles Bibliográficos
Autores principales: Sasani, Thomas A, Cone, Kelsey R, Quinlan, Aaron R, Elde, Nels C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115191/
https://www.ncbi.nlm.nih.gov/pubmed/30156554
http://dx.doi.org/10.7554/eLife.35453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115191/
https://www.ncbi.nlm.nih.gov/pubmed/30156554
http://dx.doi.org/10.7554/eLife.35453

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