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Foot-and-mouth disease virus induces lysosomal degradation of NME1 to impair p53-regulated interferon-inducible antiviral genes expression

Nucleoside diphosphate kinase 1 (NME1) is well-known as a tumor suppressor that regulates p53 function to prevent cancer metastasis and progression. However, the role of NME1 in virus-infected cells remains unknown. Here, we showed that NME1 suppresses viral replication in foot-and-mouth disease vir...

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Detalles Bibliográficos
Autores principales:	Feng, Huan-Huan, Zhu, Zi-Xiang, Cao, Wei-Jun, Yang, Fan, Zhang, Xiang-Le, Du, Xiao-Li, Zhang, Ke-Shan, Liu, Xiang-Tao, Zheng, Hai-Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115381/ https://www.ncbi.nlm.nih.gov/pubmed/30158514 http://dx.doi.org/10.1038/s41419-018-0940-z

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