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The bHLH transcription factor DEC1 promotes thyroid cancer aggressiveness by the interplay with NOTCH1

Aberrant re-activation of transcription factors occurs frequently in cancer. Recently, we found the basic helix-loop-helix transcription factors DEC1 and DEC2 significantly up-regulated in a model of highly aggressive thyroid cancer, raising the hypothesis that these factors might be part of the pro...

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Detalles Bibliográficos
Autores principales: Gallo, Cristina, Fragliasso, Valentina, Donati, Benedetta, Torricelli, Federica, Tameni, Annalisa, Piana, Simonetta, Ciarrocchi, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115386/
https://www.ncbi.nlm.nih.gov/pubmed/30158530
http://dx.doi.org/10.1038/s41419-018-0933-y

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