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The bHLH transcription factor DEC1 promotes thyroid cancer aggressiveness by the interplay with NOTCH1
Aberrant re-activation of transcription factors occurs frequently in cancer. Recently, we found the basic helix-loop-helix transcription factors DEC1 and DEC2 significantly up-regulated in a model of highly aggressive thyroid cancer, raising the hypothesis that these factors might be part of the pro...
Autores principales: | Gallo, Cristina, Fragliasso, Valentina, Donati, Benedetta, Torricelli, Federica, Tameni, Annalisa, Piana, Simonetta, Ciarrocchi, Alessia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115386/ https://www.ncbi.nlm.nih.gov/pubmed/30158530 http://dx.doi.org/10.1038/s41419-018-0933-y |
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