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A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia

BACKGROUND: Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, and MECs of the lung are rare, accounting for 0.1–0.2% of malignant lung tumors. Pulmonary MECs are commonly found in the segmental or lobar bronchi, rarely presenting as endobronchial lesions. CASE PRESENT...

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Autores principales: Omesh, Toolsie, Gupta, Ranjan, Saqi, Anjali, Burack, Joshua, Khaja, Misbahuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115606/
https://www.ncbi.nlm.nih.gov/pubmed/30175037
http://dx.doi.org/10.1016/j.rmcr.2018.08.014
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author Omesh, Toolsie
Gupta, Ranjan
Saqi, Anjali
Burack, Joshua
Khaja, Misbahuddin
author_facet Omesh, Toolsie
Gupta, Ranjan
Saqi, Anjali
Burack, Joshua
Khaja, Misbahuddin
author_sort Omesh, Toolsie
collection PubMed
description BACKGROUND: Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, and MECs of the lung are rare, accounting for 0.1–0.2% of malignant lung tumors. Pulmonary MECs are commonly found in the segmental or lobar bronchi, rarely presenting as endobronchial lesions. CASE PRESENTATION: Here we describe the case of a 21-year-old female with no comorbid conditions who presented at the emergency room with a cough, yellow phlegm, pleuritic chest pain, and a subjective fever. These symptoms had been present for approximately one week prior to the patient's arrival at the hospital. A chest X-ray revealed right lower lobe alveolar infiltrate and computed tomography of the chest showed dense consolidation of the right lower lobe with ovoid intraluminal density in the right main stem bronchus. Upon fiber optic bronchoscopy, an endobronchial lesion was found in the right main stem sparing the right upper lobe uptake. Endobronchial biopsy results was consistent with MEC of the lung. The patient underwent a bilobectomy with complete resection of the tumor. CONCLUSION: Endobronchial MEC is a rare type of salivary gland tumor. Patients with low-grade MECs have a good prognosis, whereas those with high-grade MECs, which are aggressive and associated with metastatic disease, have a poor prognosis. However, early identification and surgical resection can result in a good prognosis.
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spelling pubmed-61156062018-08-31 A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia Omesh, Toolsie Gupta, Ranjan Saqi, Anjali Burack, Joshua Khaja, Misbahuddin Respir Med Case Rep Case Report BACKGROUND: Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, and MECs of the lung are rare, accounting for 0.1–0.2% of malignant lung tumors. Pulmonary MECs are commonly found in the segmental or lobar bronchi, rarely presenting as endobronchial lesions. CASE PRESENTATION: Here we describe the case of a 21-year-old female with no comorbid conditions who presented at the emergency room with a cough, yellow phlegm, pleuritic chest pain, and a subjective fever. These symptoms had been present for approximately one week prior to the patient's arrival at the hospital. A chest X-ray revealed right lower lobe alveolar infiltrate and computed tomography of the chest showed dense consolidation of the right lower lobe with ovoid intraluminal density in the right main stem bronchus. Upon fiber optic bronchoscopy, an endobronchial lesion was found in the right main stem sparing the right upper lobe uptake. Endobronchial biopsy results was consistent with MEC of the lung. The patient underwent a bilobectomy with complete resection of the tumor. CONCLUSION: Endobronchial MEC is a rare type of salivary gland tumor. Patients with low-grade MECs have a good prognosis, whereas those with high-grade MECs, which are aggressive and associated with metastatic disease, have a poor prognosis. However, early identification and surgical resection can result in a good prognosis. Elsevier 2018-08-24 /pmc/articles/PMC6115606/ /pubmed/30175037 http://dx.doi.org/10.1016/j.rmcr.2018.08.014 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Omesh, Toolsie
Gupta, Ranjan
Saqi, Anjali
Burack, Joshua
Khaja, Misbahuddin
A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_full A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_fullStr A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_full_unstemmed A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_short A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_sort rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115606/
https://www.ncbi.nlm.nih.gov/pubmed/30175037
http://dx.doi.org/10.1016/j.rmcr.2018.08.014
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