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Red Blood Cells in Type 2 Diabetes Impair Cardiac Post-Ischemic Recovery Through an Arginase-Dependent Modulation of Nitric Oxide Synthase and Reactive Oxygen Species

This study tested the hypothesis that red blood cell (RBC) arginase represents a potential therapeutic target in ischemia-reperfusion in type 2 diabetes. Post-ischemic cardiac recovery was impaired in hearts from db/db mice compared with wild-type hearts. RBCs from mice and patients with type 2 diab...

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Detalles Bibliográficos
Autores principales:	Yang, Jiangning, Zheng, Xiaowei, Mahdi, Ali, Zhou, Zhichao, Tratsiakovich, Yahor, Jiao, Tong, Kiss, Attila, Kövamees, Oskar, Alvarsson, Michael, Catrina, Sergiu-Bogdan, Lundberg, Jon O., Brismar, Kerstin, Pernow, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	PRECLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115643/ https://www.ncbi.nlm.nih.gov/pubmed/30175269 http://dx.doi.org/10.1016/j.jacbts.2018.03.006

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