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Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes

Hypoxia-inducible factor (HIF)-1α is essential following a myocardial infarction (MI), and diabetic patients have poorer prognosis post-MI. Could HIF-1α activation be abnormal in the diabetic heart, and could metabolism be causing this? Diabetic hearts had decreased HIF-1α protein following ischemia...

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Detalles Bibliográficos
Autores principales:	Dodd, Michael S., Sousa Fialho, Maria da Luz, Montes Aparicio, Claudia N., Kerr, Matthew, Timm, Kerstin N., Griffin, Julian L., Luiken, Joost J.F.P., Glatz, Jan F.C., Tyler, Damian J., Heather, Lisa C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	PRECLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115650/ https://www.ncbi.nlm.nih.gov/pubmed/30175272 http://dx.doi.org/10.1016/j.jacbts.2018.04.005

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