Cargando…

Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring

Worldwide, childhood obesity is rapidly increasing, making it a pressing public health issue. Obesity is strongly linked to eating behaviour and energy intake but little is known about their prenatal determinants. In an exploratory study of data collected within the Amsterdam Born Children and their...

Descripción completa

Detalles Bibliográficos
Autores principales: Dieberger, Anna M., de Rooij, Susanne R., Korosi, Aniko, Vrijkotte, Tanja G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115740/
https://www.ncbi.nlm.nih.gov/pubmed/30082636
http://dx.doi.org/10.3390/nu10081026
_version_ 1783351450627211264
author Dieberger, Anna M.
de Rooij, Susanne R.
Korosi, Aniko
Vrijkotte, Tanja G. M.
author_facet Dieberger, Anna M.
de Rooij, Susanne R.
Korosi, Aniko
Vrijkotte, Tanja G. M.
author_sort Dieberger, Anna M.
collection PubMed
description Worldwide, childhood obesity is rapidly increasing, making it a pressing public health issue. Obesity is strongly linked to eating behaviour and energy intake but little is known about their prenatal determinants. In an exploratory study of data collected within the Amsterdam Born Children and their Development (ABCD) study, we hypothesized that intra-uterine exposure to increased lipids is associated with adverse eating behaviour and increased energy intake in the offspring at age 5. During early gestation, a non-fasting blood sample was taken from 1463 non-diabetic Dutch women, including: total cholesterol (TC), triglycerides (TG), free fatty acids (FFA), Apolipoprotein A1 (ApoA1) and Apolipoprotein B (ApoB). Eating behaviour, measured using the Children’s Eating Behaviour Questionnaire, included food approaching (enjoyment of food, food responsiveness) and food avoidant behaviour (satiety responsiveness, slowness of eating). Energy intake (total energy, fat and carbohydrate intake) was measured using a validated food frequency questionnaire. Associations were analysed using multivariable linear regression. Increased maternal TC concentrations were associated with lower enjoyment of food, higher satiety responsiveness and increased slowness of eating, as well as decreased kcal and fat intake in the offspring. Elevated ApoA1 was associated with increased slowness of eating, lower enjoyment of food and lower kcal, fat and carbohydrate intake. ApoB was positively associated with satiety responsiveness and slowness of eating. Higher TG concentrations were associated with higher food responsiveness. Maternal FFA did not show significant associations. Findings demonstrated that the maternal prenatal lipid profile was associated with offspring’s eating behaviour and energy intake, although not always in the hypothesized direction.
format Online
Article
Text
id pubmed-6115740
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61157402018-09-04 Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring Dieberger, Anna M. de Rooij, Susanne R. Korosi, Aniko Vrijkotte, Tanja G. M. Nutrients Article Worldwide, childhood obesity is rapidly increasing, making it a pressing public health issue. Obesity is strongly linked to eating behaviour and energy intake but little is known about their prenatal determinants. In an exploratory study of data collected within the Amsterdam Born Children and their Development (ABCD) study, we hypothesized that intra-uterine exposure to increased lipids is associated with adverse eating behaviour and increased energy intake in the offspring at age 5. During early gestation, a non-fasting blood sample was taken from 1463 non-diabetic Dutch women, including: total cholesterol (TC), triglycerides (TG), free fatty acids (FFA), Apolipoprotein A1 (ApoA1) and Apolipoprotein B (ApoB). Eating behaviour, measured using the Children’s Eating Behaviour Questionnaire, included food approaching (enjoyment of food, food responsiveness) and food avoidant behaviour (satiety responsiveness, slowness of eating). Energy intake (total energy, fat and carbohydrate intake) was measured using a validated food frequency questionnaire. Associations were analysed using multivariable linear regression. Increased maternal TC concentrations were associated with lower enjoyment of food, higher satiety responsiveness and increased slowness of eating, as well as decreased kcal and fat intake in the offspring. Elevated ApoA1 was associated with increased slowness of eating, lower enjoyment of food and lower kcal, fat and carbohydrate intake. ApoB was positively associated with satiety responsiveness and slowness of eating. Higher TG concentrations were associated with higher food responsiveness. Maternal FFA did not show significant associations. Findings demonstrated that the maternal prenatal lipid profile was associated with offspring’s eating behaviour and energy intake, although not always in the hypothesized direction. MDPI 2018-08-06 /pmc/articles/PMC6115740/ /pubmed/30082636 http://dx.doi.org/10.3390/nu10081026 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dieberger, Anna M.
de Rooij, Susanne R.
Korosi, Aniko
Vrijkotte, Tanja G. M.
Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring
title Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring
title_full Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring
title_fullStr Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring
title_full_unstemmed Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring
title_short Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring
title_sort maternal lipid concentrations during early pregnancy and eating behaviour and energy intake in the offspring
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115740/
https://www.ncbi.nlm.nih.gov/pubmed/30082636
http://dx.doi.org/10.3390/nu10081026
work_keys_str_mv AT diebergerannam maternallipidconcentrationsduringearlypregnancyandeatingbehaviourandenergyintakeintheoffspring
AT derooijsusanner maternallipidconcentrationsduringearlypregnancyandeatingbehaviourandenergyintakeintheoffspring
AT korosianiko maternallipidconcentrationsduringearlypregnancyandeatingbehaviourandenergyintakeintheoffspring
AT vrijkottetanjagm maternallipidconcentrationsduringearlypregnancyandeatingbehaviourandenergyintakeintheoffspring