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Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)

Advanced-age adults may be at risk of iron, folate, and vitamin B(12) deficiency due to low food intake and poor absorption. This study aimed to investigate the intake and adequacy of iron, folate, and vitamin B(12) and their relationship with respective biomarker status. Face-to-face interviews wit...

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Autores principales: Pillay, Danika, Wham, Carol, Moyes, Simon, Muru-Lanning, Marama, Teh, Ruth, Kerse, Ngaire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115743/
https://www.ncbi.nlm.nih.gov/pubmed/30110989
http://dx.doi.org/10.3390/nu10081090
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author Pillay, Danika
Wham, Carol
Moyes, Simon
Muru-Lanning, Marama
Teh, Ruth
Kerse, Ngaire
author_facet Pillay, Danika
Wham, Carol
Moyes, Simon
Muru-Lanning, Marama
Teh, Ruth
Kerse, Ngaire
author_sort Pillay, Danika
collection PubMed
description Advanced-age adults may be at risk of iron, folate, and vitamin B(12) deficiency due to low food intake and poor absorption. This study aimed to investigate the intake and adequacy of iron, folate, and vitamin B(12) and their relationship with respective biomarker status. Face-to-face interviews with 216 Māori and 362 non-Māori included a detailed dietary assessment using 2 × 24-h multiple pass recalls. Serum ferritin, serum iron, total iron binding capacity, transferrin saturation, red blood cell folate, serum folate, serum vitamin B(12) and hemoglobin were available at baseline. Regression techniques were used to estimate the association between dietary intake and biomarkers. The Estimated Average Requirement (EAR) was met by most participants (>88%) for dietary iron and vitamin B(12) (>74%) but less than half (>42%) for folate. Increased dietary folate intake was associated with increased red blood cell (RBC) folate for Māori (p = 0.001), non-Māori (p = 0.014) and serum folate for Māori (p < 0.001). Folate intake >215 µg/day was associated with reduced risk of deficiency in RBC folate for Māori (p = 0.001). Strategies are needed to optimize the intake and bioavailability of foods rich in folate. There were no significant associations between dietary iron and vitamin B(12) intake and their respective biomarkers, serum iron and serum vitamin B(12).
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spelling pubmed-61157432018-09-04 Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ) Pillay, Danika Wham, Carol Moyes, Simon Muru-Lanning, Marama Teh, Ruth Kerse, Ngaire Nutrients Article Advanced-age adults may be at risk of iron, folate, and vitamin B(12) deficiency due to low food intake and poor absorption. This study aimed to investigate the intake and adequacy of iron, folate, and vitamin B(12) and their relationship with respective biomarker status. Face-to-face interviews with 216 Māori and 362 non-Māori included a detailed dietary assessment using 2 × 24-h multiple pass recalls. Serum ferritin, serum iron, total iron binding capacity, transferrin saturation, red blood cell folate, serum folate, serum vitamin B(12) and hemoglobin were available at baseline. Regression techniques were used to estimate the association between dietary intake and biomarkers. The Estimated Average Requirement (EAR) was met by most participants (>88%) for dietary iron and vitamin B(12) (>74%) but less than half (>42%) for folate. Increased dietary folate intake was associated with increased red blood cell (RBC) folate for Māori (p = 0.001), non-Māori (p = 0.014) and serum folate for Māori (p < 0.001). Folate intake >215 µg/day was associated with reduced risk of deficiency in RBC folate for Māori (p = 0.001). Strategies are needed to optimize the intake and bioavailability of foods rich in folate. There were no significant associations between dietary iron and vitamin B(12) intake and their respective biomarkers, serum iron and serum vitamin B(12). MDPI 2018-08-14 /pmc/articles/PMC6115743/ /pubmed/30110989 http://dx.doi.org/10.3390/nu10081090 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pillay, Danika
Wham, Carol
Moyes, Simon
Muru-Lanning, Marama
Teh, Ruth
Kerse, Ngaire
Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)
title Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)
title_full Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)
title_fullStr Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)
title_full_unstemmed Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)
title_short Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B(12) in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)
title_sort intakes, adequacy, and biomarker status of iron, folate, and vitamin b(12) in māori and non-māori octogenarians: life and living in advanced age: a cohort study in new zealand (lilacs nz)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115743/
https://www.ncbi.nlm.nih.gov/pubmed/30110989
http://dx.doi.org/10.3390/nu10081090
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