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Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City
Adequate nutrition is important for neurodevelopment. Although nutrients are ingested in combination, the impact of specific nutrients within the context of a nutrient mixture has not been studied with respect to health, such as neurodevelopment. Therefore, we examined the impact of prenatal and chi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115750/ https://www.ncbi.nlm.nih.gov/pubmed/30111728 http://dx.doi.org/10.3390/nu10081093 |
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author | Malin, Ashley J. Busgang, Stefanie A. Cantoral, Alejandra J. Svensson, Katherine Orjuela, Manuela A. Pantic, Ivan Schnaas, Lourdes Oken, Emily Baccarelli, Andrea A. Téllez-Rojo, Martha M. Wright, Robert O. Gennings, Chris |
author_facet | Malin, Ashley J. Busgang, Stefanie A. Cantoral, Alejandra J. Svensson, Katherine Orjuela, Manuela A. Pantic, Ivan Schnaas, Lourdes Oken, Emily Baccarelli, Andrea A. Téllez-Rojo, Martha M. Wright, Robert O. Gennings, Chris |
author_sort | Malin, Ashley J. |
collection | PubMed |
description | Adequate nutrition is important for neurodevelopment. Although nutrients are ingested in combination, the impact of specific nutrients within the context of a nutrient mixture has not been studied with respect to health, such as neurodevelopment. Therefore, we examined the impact of prenatal and childhood nutrient mixtures on neurodevelopmental outcomes. Participants included mother–child pairs in the Programming Research in Obesity, Growth, Environment, and Social Stress (PROGRESS) prospective birth cohort in Mexico City. We assessed prenatal and child micro- and macronutrient profiles among 65 and 329 children, respectively, via food frequency questionnaires. Neurodevelopmental outcomes of 4–6 year-old children were measured using the McCarthy Scales of Children’s Abilities (MSCA). We conducted weighted quantile sum (WQS) regression analyses to calculate indices reflecting “good” and “poor” prenatal and childhood nutrition. After adjusting for maternal education, socioeconomic status, the Home Observation for Measurement of the Environment (HOME) score, and total caloric intake, the good prenatal and childhood nutrition indices predicted more favorable neurodevelopment, while both poor nutrition indices predicted poorer neurodevelopment. These associations were stronger in prenatal than childhood models. Monounsaturated fats predicted various neurodevelopmental abilities relatively strongly in both models. Prenatal and childhood consumption of combinations of beneficial nutrients may contribute to more favorable neurodevelopment. |
format | Online Article Text |
id | pubmed-6115750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61157502018-09-04 Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City Malin, Ashley J. Busgang, Stefanie A. Cantoral, Alejandra J. Svensson, Katherine Orjuela, Manuela A. Pantic, Ivan Schnaas, Lourdes Oken, Emily Baccarelli, Andrea A. Téllez-Rojo, Martha M. Wright, Robert O. Gennings, Chris Nutrients Article Adequate nutrition is important for neurodevelopment. Although nutrients are ingested in combination, the impact of specific nutrients within the context of a nutrient mixture has not been studied with respect to health, such as neurodevelopment. Therefore, we examined the impact of prenatal and childhood nutrient mixtures on neurodevelopmental outcomes. Participants included mother–child pairs in the Programming Research in Obesity, Growth, Environment, and Social Stress (PROGRESS) prospective birth cohort in Mexico City. We assessed prenatal and child micro- and macronutrient profiles among 65 and 329 children, respectively, via food frequency questionnaires. Neurodevelopmental outcomes of 4–6 year-old children were measured using the McCarthy Scales of Children’s Abilities (MSCA). We conducted weighted quantile sum (WQS) regression analyses to calculate indices reflecting “good” and “poor” prenatal and childhood nutrition. After adjusting for maternal education, socioeconomic status, the Home Observation for Measurement of the Environment (HOME) score, and total caloric intake, the good prenatal and childhood nutrition indices predicted more favorable neurodevelopment, while both poor nutrition indices predicted poorer neurodevelopment. These associations were stronger in prenatal than childhood models. Monounsaturated fats predicted various neurodevelopmental abilities relatively strongly in both models. Prenatal and childhood consumption of combinations of beneficial nutrients may contribute to more favorable neurodevelopment. MDPI 2018-08-15 /pmc/articles/PMC6115750/ /pubmed/30111728 http://dx.doi.org/10.3390/nu10081093 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Malin, Ashley J. Busgang, Stefanie A. Cantoral, Alejandra J. Svensson, Katherine Orjuela, Manuela A. Pantic, Ivan Schnaas, Lourdes Oken, Emily Baccarelli, Andrea A. Téllez-Rojo, Martha M. Wright, Robert O. Gennings, Chris Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City |
title | Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City |
title_full | Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City |
title_fullStr | Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City |
title_full_unstemmed | Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City |
title_short | Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City |
title_sort | quality of prenatal and childhood diet predicts neurodevelopmental outcomes among children in mexico city |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115750/ https://www.ncbi.nlm.nih.gov/pubmed/30111728 http://dx.doi.org/10.3390/nu10081093 |
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