Cargando…

Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City

Adequate nutrition is important for neurodevelopment. Although nutrients are ingested in combination, the impact of specific nutrients within the context of a nutrient mixture has not been studied with respect to health, such as neurodevelopment. Therefore, we examined the impact of prenatal and chi...

Descripción completa

Detalles Bibliográficos
Autores principales: Malin, Ashley J., Busgang, Stefanie A., Cantoral, Alejandra J., Svensson, Katherine, Orjuela, Manuela A., Pantic, Ivan, Schnaas, Lourdes, Oken, Emily, Baccarelli, Andrea A., Téllez-Rojo, Martha M., Wright, Robert O., Gennings, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115750/
https://www.ncbi.nlm.nih.gov/pubmed/30111728
http://dx.doi.org/10.3390/nu10081093
_version_ 1783351452930932736
author Malin, Ashley J.
Busgang, Stefanie A.
Cantoral, Alejandra J.
Svensson, Katherine
Orjuela, Manuela A.
Pantic, Ivan
Schnaas, Lourdes
Oken, Emily
Baccarelli, Andrea A.
Téllez-Rojo, Martha M.
Wright, Robert O.
Gennings, Chris
author_facet Malin, Ashley J.
Busgang, Stefanie A.
Cantoral, Alejandra J.
Svensson, Katherine
Orjuela, Manuela A.
Pantic, Ivan
Schnaas, Lourdes
Oken, Emily
Baccarelli, Andrea A.
Téllez-Rojo, Martha M.
Wright, Robert O.
Gennings, Chris
author_sort Malin, Ashley J.
collection PubMed
description Adequate nutrition is important for neurodevelopment. Although nutrients are ingested in combination, the impact of specific nutrients within the context of a nutrient mixture has not been studied with respect to health, such as neurodevelopment. Therefore, we examined the impact of prenatal and childhood nutrient mixtures on neurodevelopmental outcomes. Participants included mother–child pairs in the Programming Research in Obesity, Growth, Environment, and Social Stress (PROGRESS) prospective birth cohort in Mexico City. We assessed prenatal and child micro- and macronutrient profiles among 65 and 329 children, respectively, via food frequency questionnaires. Neurodevelopmental outcomes of 4–6 year-old children were measured using the McCarthy Scales of Children’s Abilities (MSCA). We conducted weighted quantile sum (WQS) regression analyses to calculate indices reflecting “good” and “poor” prenatal and childhood nutrition. After adjusting for maternal education, socioeconomic status, the Home Observation for Measurement of the Environment (HOME) score, and total caloric intake, the good prenatal and childhood nutrition indices predicted more favorable neurodevelopment, while both poor nutrition indices predicted poorer neurodevelopment. These associations were stronger in prenatal than childhood models. Monounsaturated fats predicted various neurodevelopmental abilities relatively strongly in both models. Prenatal and childhood consumption of combinations of beneficial nutrients may contribute to more favorable neurodevelopment.
format Online
Article
Text
id pubmed-6115750
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61157502018-09-04 Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City Malin, Ashley J. Busgang, Stefanie A. Cantoral, Alejandra J. Svensson, Katherine Orjuela, Manuela A. Pantic, Ivan Schnaas, Lourdes Oken, Emily Baccarelli, Andrea A. Téllez-Rojo, Martha M. Wright, Robert O. Gennings, Chris Nutrients Article Adequate nutrition is important for neurodevelopment. Although nutrients are ingested in combination, the impact of specific nutrients within the context of a nutrient mixture has not been studied with respect to health, such as neurodevelopment. Therefore, we examined the impact of prenatal and childhood nutrient mixtures on neurodevelopmental outcomes. Participants included mother–child pairs in the Programming Research in Obesity, Growth, Environment, and Social Stress (PROGRESS) prospective birth cohort in Mexico City. We assessed prenatal and child micro- and macronutrient profiles among 65 and 329 children, respectively, via food frequency questionnaires. Neurodevelopmental outcomes of 4–6 year-old children were measured using the McCarthy Scales of Children’s Abilities (MSCA). We conducted weighted quantile sum (WQS) regression analyses to calculate indices reflecting “good” and “poor” prenatal and childhood nutrition. After adjusting for maternal education, socioeconomic status, the Home Observation for Measurement of the Environment (HOME) score, and total caloric intake, the good prenatal and childhood nutrition indices predicted more favorable neurodevelopment, while both poor nutrition indices predicted poorer neurodevelopment. These associations were stronger in prenatal than childhood models. Monounsaturated fats predicted various neurodevelopmental abilities relatively strongly in both models. Prenatal and childhood consumption of combinations of beneficial nutrients may contribute to more favorable neurodevelopment. MDPI 2018-08-15 /pmc/articles/PMC6115750/ /pubmed/30111728 http://dx.doi.org/10.3390/nu10081093 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Malin, Ashley J.
Busgang, Stefanie A.
Cantoral, Alejandra J.
Svensson, Katherine
Orjuela, Manuela A.
Pantic, Ivan
Schnaas, Lourdes
Oken, Emily
Baccarelli, Andrea A.
Téllez-Rojo, Martha M.
Wright, Robert O.
Gennings, Chris
Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City
title Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City
title_full Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City
title_fullStr Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City
title_full_unstemmed Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City
title_short Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City
title_sort quality of prenatal and childhood diet predicts neurodevelopmental outcomes among children in mexico city
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115750/
https://www.ncbi.nlm.nih.gov/pubmed/30111728
http://dx.doi.org/10.3390/nu10081093
work_keys_str_mv AT malinashleyj qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT busgangstefaniea qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT cantoralalejandraj qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT svenssonkatherine qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT orjuelamanuelaa qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT panticivan qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT schnaaslourdes qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT okenemily qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT baccarelliandreaa qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT tellezrojomartham qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT wrightroberto qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity
AT genningschris qualityofprenatalandchildhooddietpredictsneurodevelopmentaloutcomesamongchildreninmexicocity