Cargando…
Mediterranean Diet and Bladder Cancer Risk in Italy
Previous studies have reported that Mediterranean diet is inversely related to the risk of several neoplasms; however, limited epidemiological data are available for bladder cancer. Thus, we examined the association between Mediterranean diet and this neoplasm in an Italian multicentric case-control...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115823/ https://www.ncbi.nlm.nih.gov/pubmed/30103393 http://dx.doi.org/10.3390/nu10081061 |
_version_ | 1783351470343585792 |
---|---|
author | Bravi, Francesca Spei, Maria-Eleni Polesel, Jerry Di Maso, Matteo Montella, Maurizio Ferraroni, Monica Serraino, Diego Libra, Massimo Negri, Eva La Vecchia, Carlo Turati, Federica |
author_facet | Bravi, Francesca Spei, Maria-Eleni Polesel, Jerry Di Maso, Matteo Montella, Maurizio Ferraroni, Monica Serraino, Diego Libra, Massimo Negri, Eva La Vecchia, Carlo Turati, Federica |
author_sort | Bravi, Francesca |
collection | PubMed |
description | Previous studies have reported that Mediterranean diet is inversely related to the risk of several neoplasms; however, limited epidemiological data are available for bladder cancer. Thus, we examined the association between Mediterranean diet and this neoplasm in an Italian multicentric case-control study consisting of 690 bladder cancer cases and 665 controls. We assessed the adherence to the Mediterranean diet via a Mediterranean Diet Score (MDS), which represents the major characteristics of the Mediterranean diet and ranges from 0 to 9 (from minimal to maximal adherence, respectively). We derived odds ratios (ORs) of bladder cancer according to the MDS score from multiple logistic regression models, allowing for major confounding factors. The ORs of bladder cancer were 0.72 (95% confidence interval, CI, 0.54–0.98) for MDS of 4–5 and 0.66 (95% CI, 0.47–0.93) for MDS of 6–9 (p for trend = 0.02) compared to MDS = 0–3. Results were similar in strata of sex, age, and education, while the risk appeared somewhat lower in never-smokers and patients with pT1–pT4 bladder carcinomas. Among individual components of the MDS, we observed inverse associations for greater consumption of legumes, vegetables, and fish. In our study, which was carried out on an Italian population, the higher adherence to the Mediterranean diet was related to a lower risk of bladder cancer. |
format | Online Article Text |
id | pubmed-6115823 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61158232018-09-04 Mediterranean Diet and Bladder Cancer Risk in Italy Bravi, Francesca Spei, Maria-Eleni Polesel, Jerry Di Maso, Matteo Montella, Maurizio Ferraroni, Monica Serraino, Diego Libra, Massimo Negri, Eva La Vecchia, Carlo Turati, Federica Nutrients Article Previous studies have reported that Mediterranean diet is inversely related to the risk of several neoplasms; however, limited epidemiological data are available for bladder cancer. Thus, we examined the association between Mediterranean diet and this neoplasm in an Italian multicentric case-control study consisting of 690 bladder cancer cases and 665 controls. We assessed the adherence to the Mediterranean diet via a Mediterranean Diet Score (MDS), which represents the major characteristics of the Mediterranean diet and ranges from 0 to 9 (from minimal to maximal adherence, respectively). We derived odds ratios (ORs) of bladder cancer according to the MDS score from multiple logistic regression models, allowing for major confounding factors. The ORs of bladder cancer were 0.72 (95% confidence interval, CI, 0.54–0.98) for MDS of 4–5 and 0.66 (95% CI, 0.47–0.93) for MDS of 6–9 (p for trend = 0.02) compared to MDS = 0–3. Results were similar in strata of sex, age, and education, while the risk appeared somewhat lower in never-smokers and patients with pT1–pT4 bladder carcinomas. Among individual components of the MDS, we observed inverse associations for greater consumption of legumes, vegetables, and fish. In our study, which was carried out on an Italian population, the higher adherence to the Mediterranean diet was related to a lower risk of bladder cancer. MDPI 2018-08-10 /pmc/articles/PMC6115823/ /pubmed/30103393 http://dx.doi.org/10.3390/nu10081061 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bravi, Francesca Spei, Maria-Eleni Polesel, Jerry Di Maso, Matteo Montella, Maurizio Ferraroni, Monica Serraino, Diego Libra, Massimo Negri, Eva La Vecchia, Carlo Turati, Federica Mediterranean Diet and Bladder Cancer Risk in Italy |
title | Mediterranean Diet and Bladder Cancer Risk in Italy |
title_full | Mediterranean Diet and Bladder Cancer Risk in Italy |
title_fullStr | Mediterranean Diet and Bladder Cancer Risk in Italy |
title_full_unstemmed | Mediterranean Diet and Bladder Cancer Risk in Italy |
title_short | Mediterranean Diet and Bladder Cancer Risk in Italy |
title_sort | mediterranean diet and bladder cancer risk in italy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115823/ https://www.ncbi.nlm.nih.gov/pubmed/30103393 http://dx.doi.org/10.3390/nu10081061 |
work_keys_str_mv | AT bravifrancesca mediterraneandietandbladdercancerriskinitaly AT speimariaeleni mediterraneandietandbladdercancerriskinitaly AT poleseljerry mediterraneandietandbladdercancerriskinitaly AT dimasomatteo mediterraneandietandbladdercancerriskinitaly AT montellamaurizio mediterraneandietandbladdercancerriskinitaly AT ferraronimonica mediterraneandietandbladdercancerriskinitaly AT serrainodiego mediterraneandietandbladdercancerriskinitaly AT libramassimo mediterraneandietandbladdercancerriskinitaly AT negrieva mediterraneandietandbladdercancerriskinitaly AT lavecchiacarlo mediterraneandietandbladdercancerriskinitaly AT turatifederica mediterraneandietandbladdercancerriskinitaly |