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Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People

Fat-to-muscle ratio has been proposed as an alternative approach for assessing body fat. The objective of this study was to explore fat-to-muscle ratio thresholds in metabolic syndrome (MetS) diagnosis; it was hypothesised that the fat-to-muscle ratio is a good predictive indicator of MetS in a larg...

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Autores principales: Ramírez-Vélez, Robinson, Carrillo, Hugo Alejandro, Correa-Bautista, Jorge Enrique, Schmidt-RioValle, Jacqueline, González-Jiménez, Emilio, Correa-Rodríguez, María, González-Ruíz, Katherine, García-Hermoso, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115891/
https://www.ncbi.nlm.nih.gov/pubmed/30087234
http://dx.doi.org/10.3390/nu10081027
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author Ramírez-Vélez, Robinson
Carrillo, Hugo Alejandro
Correa-Bautista, Jorge Enrique
Schmidt-RioValle, Jacqueline
González-Jiménez, Emilio
Correa-Rodríguez, María
González-Ruíz, Katherine
García-Hermoso, Antonio
author_facet Ramírez-Vélez, Robinson
Carrillo, Hugo Alejandro
Correa-Bautista, Jorge Enrique
Schmidt-RioValle, Jacqueline
González-Jiménez, Emilio
Correa-Rodríguez, María
González-Ruíz, Katherine
García-Hermoso, Antonio
author_sort Ramírez-Vélez, Robinson
collection PubMed
description Fat-to-muscle ratio has been proposed as an alternative approach for assessing body fat. The objective of this study was to explore fat-to-muscle ratio thresholds in metabolic syndrome (MetS) diagnosis; it was hypothesised that the fat-to-muscle ratio is a good predictive indicator of MetS in a large population of young Colombian adults. For this purpose, a cross-sectional study was conducted on 1416 subjects (66.6% female), aged from 18.1 to 25.1. As part of the study, measurements of the subjects’ anthropometric indicators, serum lipid indices, blood pressure, and fasting plasma glucose were taken. Body composition was measured through bioelectrical impedance analysis (BIA). A new variable (ratio of fat mass to muscle mass, in kg) was calculated. Following the International Diabetes Federation (IDF) definition, MetS includes three or more metabolic abnormalities. Receiver operating characteristic (ROC) curves and logistic regression determined the discriminatory ability of the fat-to-muscle ratio to predict MetS. According to the IDF, the best fat-to-muscle ratio cut-off point for detecting MetS in men was 0.225 kg, with an area under the curve (AUC) of 0.83, sensitivity of 80%, and specificity of 70%. For women, the fat-to-muscle ratio cut-off point was 0.495 kg, the AUC was 0.88, and the sensitivity and specificity were 82% and 80%, respectively. In conclusion, our results showed that the fat-to-muscle ratio cut-off points from ROC analyses demonstrate good discriminatory power for detecting MetS in young Colombian adults.
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spelling pubmed-61158912018-09-04 Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People Ramírez-Vélez, Robinson Carrillo, Hugo Alejandro Correa-Bautista, Jorge Enrique Schmidt-RioValle, Jacqueline González-Jiménez, Emilio Correa-Rodríguez, María González-Ruíz, Katherine García-Hermoso, Antonio Nutrients Article Fat-to-muscle ratio has been proposed as an alternative approach for assessing body fat. The objective of this study was to explore fat-to-muscle ratio thresholds in metabolic syndrome (MetS) diagnosis; it was hypothesised that the fat-to-muscle ratio is a good predictive indicator of MetS in a large population of young Colombian adults. For this purpose, a cross-sectional study was conducted on 1416 subjects (66.6% female), aged from 18.1 to 25.1. As part of the study, measurements of the subjects’ anthropometric indicators, serum lipid indices, blood pressure, and fasting plasma glucose were taken. Body composition was measured through bioelectrical impedance analysis (BIA). A new variable (ratio of fat mass to muscle mass, in kg) was calculated. Following the International Diabetes Federation (IDF) definition, MetS includes three or more metabolic abnormalities. Receiver operating characteristic (ROC) curves and logistic regression determined the discriminatory ability of the fat-to-muscle ratio to predict MetS. According to the IDF, the best fat-to-muscle ratio cut-off point for detecting MetS in men was 0.225 kg, with an area under the curve (AUC) of 0.83, sensitivity of 80%, and specificity of 70%. For women, the fat-to-muscle ratio cut-off point was 0.495 kg, the AUC was 0.88, and the sensitivity and specificity were 82% and 80%, respectively. In conclusion, our results showed that the fat-to-muscle ratio cut-off points from ROC analyses demonstrate good discriminatory power for detecting MetS in young Colombian adults. MDPI 2018-08-07 /pmc/articles/PMC6115891/ /pubmed/30087234 http://dx.doi.org/10.3390/nu10081027 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ramírez-Vélez, Robinson
Carrillo, Hugo Alejandro
Correa-Bautista, Jorge Enrique
Schmidt-RioValle, Jacqueline
González-Jiménez, Emilio
Correa-Rodríguez, María
González-Ruíz, Katherine
García-Hermoso, Antonio
Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People
title Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People
title_full Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People
title_fullStr Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People
title_full_unstemmed Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People
title_short Fat-to-Muscle Ratio: A New Anthropometric Indicator as a Screening Tool for Metabolic Syndrome in Young Colombian People
title_sort fat-to-muscle ratio: a new anthropometric indicator as a screening tool for metabolic syndrome in young colombian people
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115891/
https://www.ncbi.nlm.nih.gov/pubmed/30087234
http://dx.doi.org/10.3390/nu10081027
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