A Herpes Simplex Virus Thymidine Kinase-Induced Mouse Model of Hepatocellular Carcinoma Associated with Up-Regulated Immune-Inflammatory-Related Signals

Inflammation and fibrosis in human liver are often precursors to hepatocellular carcinoma (HCC), yet none of them is easily modeled in animals. We previously generated transgenic mice with hepatocyte-specific expressed herpes simplex virus thymidine kinase (HSV-tk). These mice would develop hepatiti...

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Detalles Bibliográficos
Autores principales: Gong, Zhijuan, Ma, Qingwen, Wang, Xujun, Cai, Qin, Gong, Xiuli, Genchev, Georgi Z., Lu, Hui, Zeng, Fanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115908/
https://www.ncbi.nlm.nih.gov/pubmed/30060537
http://dx.doi.org/10.3390/genes9080380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115908/
https://www.ncbi.nlm.nih.gov/pubmed/30060537
http://dx.doi.org/10.3390/genes9080380

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