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Insights into the Voltage Regulation Mechanism of the Pore-Forming Toxin Lysenin

Lysenin, a pore forming toxin (PFT) extracted from Eisenia fetida, inserts voltage-regulated channels into artificial lipid membranes containing sphingomyelin. The voltage-induced gating leads to a strong static hysteresis in conductance, which endows lysenin with molecular memory capabilities. To e...

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Detalles Bibliográficos
Autores principales: Bryant, Sheenah Lynn, Clark, Tyler, Thomas, Christopher Alex, Ware, Kaitlyn Summer, Bogard, Andrew, Calzacorta, Colleen, Prather, Daniel, Fologea, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115918/
https://www.ncbi.nlm.nih.gov/pubmed/30126104
http://dx.doi.org/10.3390/toxins10080334