Cargando…

Insights into the Voltage Regulation Mechanism of the Pore-Forming Toxin Lysenin

Lysenin, a pore forming toxin (PFT) extracted from Eisenia fetida, inserts voltage-regulated channels into artificial lipid membranes containing sphingomyelin. The voltage-induced gating leads to a strong static hysteresis in conductance, which endows lysenin with molecular memory capabilities. To e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bryant, Sheenah Lynn, Clark, Tyler, Thomas, Christopher Alex, Ware, Kaitlyn Summer, Bogard, Andrew, Calzacorta, Colleen, Prather, Daniel, Fologea, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115918/ https://www.ncbi.nlm.nih.gov/pubmed/30126104 http://dx.doi.org/10.3390/toxins10080334

Ejemplares similares

Temporary Membrane Permeabilization via the Pore-Forming Toxin Lysenin
por: Shrestha, Nisha, et al.
Publicado: (2020)

Cationic Polymers Inhibit the Conductance of Lysenin Channels
por: Fologea, Daniel, et al.
Publicado: (2013)

ZnO nanoparticles modulate the ionic transport and voltage regulation of lysenin nanochannels
por: Bryant, Sheenah L., et al.
Publicado: (2017)

Stochastic sensing of Angiotensin II with lysenin channels
por: Shrestha, Nisha, et al.
Publicado: (2017)

Modulation of Voltage-Gating and Hysteresis of Lysenin Channels by Cu(2+) Ions
por: Bogard, Andrew, et al.
Publicado: (2023)

Lysenin Channels as Sensors for Ions and Molecules
por: Bogard, Andrew, et al.
Publicado: (2020)

Liposomes Prevent In Vitro Hemolysis Induced by Streptolysin O and Lysenin
por: Ayllon, Marcelo, et al.
Publicado: (2021)

Earthworm-Derived Pore-Forming Toxin Lysenin and Screening of Its Inhibitors
por: Sukumwang, Neelanun, et al.
Publicado: (2013)

The Ionic Selectivity of Lysenin Channels in Open and Sub-Conducting States
por: Bogard, Andrew, et al.
Publicado: (2021)

An Effective Electric Dipole Model for Voltage-induced Gating Mechanism of Lysenin
por: Faouri, Radwan Al, et al.
Publicado: (2019)

Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins And Its Mode of Sphingomyelin Recognition
por: De Colibus, Luigi, et al.
Publicado: (2012)

Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein
por: Bokori-Brown, Monika, et al.
Publicado: (2016)

Hypo-Osmotic Stress and Pore-Forming Toxins Adjust the Lipid Order in Sheep Red Blood Cell Membranes
por: Whiting, Rose, et al.
Publicado: (2023)

Insight into the Structural Dynamics of the Lysenin During Prepore-to-Pore Transition Using Hydrogen–Deuterium Exchange Mass Spectrometry
por: Kulma, Magdalena, et al.
Publicado: (2019)

Bacterial pore-forming toxins
por: Ulhuq, Fatima R., et al.
Publicado: (2022)

Membrane perforation by the pore-forming toxin pneumolysin
por: Vögele, Martin, et al.
Publicado: (2019)

The MACPF/CDC family of pore-forming toxins
por: Rosado, Carlos J, et al.
Publicado: (2008)

Role of Pore-Forming Toxins in Neonatal Sepsis
por: Sonnen, Andreas F.-P., et al.
Publicado: (2013)

Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?
por: Ostolaza, Helena, et al.
Publicado: (2019)

A biomimetic nanosponge that absorbs pore-forming toxins
por: Hu, Che-Ming J., et al.
Publicado: (2013)

Cellular Entry of Binary and Pore-Forming Bacterial Toxins
por: Ladokhin, Alexey S.
Publicado: (2017)

Structural Basis of the Pore-Forming Toxin/Membrane Interaction
por: Li, Yajuan, et al.
Publicado: (2021)

Single channel properties of lysenin measured in artificial lipid bilayers and their applications to biomolecule detection
por: AOKI, Takaaki, et al.
Publicado: (2010)

Rapid Production and Purification of Dye-Loaded Liposomes by Electrodialysis-Driven Depletion
por: Abatchev, Gamid, et al.
Publicado: (2021)

Pro-autophagic signal induction by bacterial pore-forming toxins
por: Kloft, Nicole, et al.
Publicado: (2010)

Global Functional Analyses of Cellular Responses to Pore-Forming Toxins
por: Kao, Cheng-Yuan, et al.
Publicado: (2011)

Staphylococcal Bicomponent Pore-Forming Toxins: Targets for Prophylaxis and Immunotherapy
por: Aman, M. Javad, et al.
Publicado: (2014)

Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins
por: Etxaniz, Asier, et al.
Publicado: (2018)

Response of Cellular Innate Immunity to Cnidarian Pore-Forming Toxins
por: Yap, Wei Yuen, et al.
Publicado: (2018)

Disarming Pore-Forming Toxins with Biomimetic Nanosponges in Intraocular Infections
por: Coburn, Phillip S., et al.
Publicado: (2019)

Oxysterols Protect Epithelial Cells Against Pore-Forming Toxins
por: Ormsby, Thomas J. R., et al.
Publicado: (2022)

The Importance of Pore-Forming Toxins in Multiple Organ Injury and Dysfunction
por: Abrams, Simon T., et al.
Publicado: (2022)

Curcumin Inhibits Membrane-Damaging Pore-Forming Function of the β-Barrel Pore-Forming Toxin Vibrio cholerae Cytolysin
por: Singh, Mahendra, et al.
Publicado: (2022)

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel
por: Banerjee, Anirban, et al.
Publicado: (2013)

Role for caspase-2 during pore-forming toxin-mediated apoptosis
por: Imre, Gergely, et al.
Publicado: (2012)

Antibody-based intervention against the pore-forming toxins of Staphylococcus aureus
por: Thomsen, Isaac P.
Publicado: (2018)

Control of cytoskeletal dynamics during cellular responses to pore forming toxins
por: Mesquita, Francisco Sarmento, et al.
Publicado: (2017)

Mechanisms protecting host cells against bacterial pore-forming toxins
por: Brito, Cláudia, et al.
Publicado: (2018)

Functional Consequences of Calcium Influx Promoted by Bacterial Pore-Forming Toxins
por: Bouillot, Stéphanie, et al.
Publicado: (2018)

Pore-forming Esx proteins mediate toxin secretion by Mycobacterium tuberculosis
por: Tak, Uday, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_goh862eusev5sd22askk8bej0d