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Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization

Prevention of severe lower respiratory tract infections in infants caused by the human respiratory syncytial virus (hRSV) remains a major public health priority. Currently, the major focus of vaccine development relies on the RSV fusion (F) protein since it is the main target protein for neutralizin...

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Detalles Bibliográficos
Autores principales: Leemans, Annelies, Boeren, Marlies, Van der Gucht, Winke, Pintelon, Isabel, Roose, Kenny, Schepens, Bert, Saelens, Xavier, Bailey, Dalan, Martinet, Wim, Caljon, Guy, Maes, Louis, Cos, Paul, Delputte, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115940/
https://www.ncbi.nlm.nih.gov/pubmed/30110893
http://dx.doi.org/10.3390/v10080426