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Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization
Prevention of severe lower respiratory tract infections in infants caused by the human respiratory syncytial virus (hRSV) remains a major public health priority. Currently, the major focus of vaccine development relies on the RSV fusion (F) protein since it is the main target protein for neutralizin...
Autores principales: | Leemans, Annelies, Boeren, Marlies, Van der Gucht, Winke, Pintelon, Isabel, Roose, Kenny, Schepens, Bert, Saelens, Xavier, Bailey, Dalan, Martinet, Wim, Caljon, Guy, Maes, Louis, Cos, Paul, Delputte, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115940/ https://www.ncbi.nlm.nih.gov/pubmed/30110893 http://dx.doi.org/10.3390/v10080426 |
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