LY2157299 Monohydrate, a TGF-βR1 Inhibitor, Suppresses Tumor Growth and Ascites Development in Ovarian Cancer

Transforming growth factor beta (TGF-β) signaling has pleiotropic functions regulating cancer initiation, development, and metastasis, and also plays important roles in the interaction between stromal and cancer cells, making the pathway a potential therapeutic target. LY2157299 monohydrate (LY), an...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Hou, Xiaonan, Evans, Bradley J., VanBlaricom, Jamison L., Weroha, Saravut J., Cliby, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115954/
https://www.ncbi.nlm.nih.gov/pubmed/30087253
http://dx.doi.org/10.3390/cancers10080260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115954/
https://www.ncbi.nlm.nih.gov/pubmed/30087253
http://dx.doi.org/10.3390/cancers10080260

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