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LY2157299 Monohydrate, a TGF-βR1 Inhibitor, Suppresses Tumor Growth and Ascites Development in Ovarian Cancer
Transforming growth factor beta (TGF-β) signaling has pleiotropic functions regulating cancer initiation, development, and metastasis, and also plays important roles in the interaction between stromal and cancer cells, making the pathway a potential therapeutic target. LY2157299 monohydrate (LY), an...
Autores principales: | Zhang, Qing, Hou, Xiaonan, Evans, Bradley J., VanBlaricom, Jamison L., Weroha, Saravut J., Cliby, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115954/ https://www.ncbi.nlm.nih.gov/pubmed/30087253 http://dx.doi.org/10.3390/cancers10080260 |
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