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Removal of the C6 Vaccinia Virus Interferon-β Inhibitor in the Hepatitis C Vaccine Candidate MVA-HCV Elicited in Mice High Immunogenicity in Spite of Reduced Host Gene Expression
Hepatitis C virus (HCV) represents a major global health problem for which a vaccine is not available. Modified vaccinia virus Ankara (MVA)-HCV is a unique HCV vaccine candidate based in the modified vaccinia virus Ankara (MVA) vector expressing the nearly full-length genome of HCV genotype 1a that...
Autores principales: | Q. Marín, María, Pérez, Patricia, Gómez, Carmen E., S. Sorzano, Carlos Óscar, Esteban, Mariano, García-Arriaza, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116028/ https://www.ncbi.nlm.nih.gov/pubmed/30096846 http://dx.doi.org/10.3390/v10080414 |
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