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Analysis of Candidate Idarubicin Drug Resistance Genes in MOLT-3 Cells Using Exome Nuclear DNA

Various gene alterations related to acute leukemia are reported to be involved in drug resistance. We investigated idarubicin (IDR) resistance using exome nuclear DNA analyses of the human acute leukemia cell line MOLT-3 and the derived IDR-resistant cell line MOLT-3/IDR. We detected mutations in MO...

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Detalles Bibliográficos
Autores principales:	Komiyama, Tomoyoshi, Ogura, Atsushi, Kajiwara, Takehito, Okada, Yoshinori, Kobayashi, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116115/ https://www.ncbi.nlm.nih.gov/pubmed/30071629 http://dx.doi.org/10.3390/genes9080390

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