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Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis

Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave...

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Detalles Bibliográficos
Autores principales: Mangeolle, Tristan, Yakavets, Ilya, Marchal, Sophie, Debayle, Manon, Pons, Thomas, Bezdetnaya, Lina, Marchal, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116267/
https://www.ncbi.nlm.nih.gov/pubmed/30050022
http://dx.doi.org/10.3390/nano8080572
Descripción
Sumario:Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application.