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Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis

Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave...

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Autores principales: Mangeolle, Tristan, Yakavets, Ilya, Marchal, Sophie, Debayle, Manon, Pons, Thomas, Bezdetnaya, Lina, Marchal, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116267/
https://www.ncbi.nlm.nih.gov/pubmed/30050022
http://dx.doi.org/10.3390/nano8080572
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author Mangeolle, Tristan
Yakavets, Ilya
Marchal, Sophie
Debayle, Manon
Pons, Thomas
Bezdetnaya, Lina
Marchal, Frédéric
author_facet Mangeolle, Tristan
Yakavets, Ilya
Marchal, Sophie
Debayle, Manon
Pons, Thomas
Bezdetnaya, Lina
Marchal, Frédéric
author_sort Mangeolle, Tristan
collection PubMed
description Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application.
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spelling pubmed-61162672018-08-31 Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis Mangeolle, Tristan Yakavets, Ilya Marchal, Sophie Debayle, Manon Pons, Thomas Bezdetnaya, Lina Marchal, Frédéric Nanomaterials (Basel) Review Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application. MDPI 2018-07-26 /pmc/articles/PMC6116267/ /pubmed/30050022 http://dx.doi.org/10.3390/nano8080572 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mangeolle, Tristan
Yakavets, Ilya
Marchal, Sophie
Debayle, Manon
Pons, Thomas
Bezdetnaya, Lina
Marchal, Frédéric
Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis
title Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis
title_full Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis
title_fullStr Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis
title_full_unstemmed Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis
title_short Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis
title_sort fluorescent nanoparticles for the guided surgery of ovarian peritoneal carcinomatosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116267/
https://www.ncbi.nlm.nih.gov/pubmed/30050022
http://dx.doi.org/10.3390/nano8080572
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