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Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis
Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116267/ https://www.ncbi.nlm.nih.gov/pubmed/30050022 http://dx.doi.org/10.3390/nano8080572 |
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author | Mangeolle, Tristan Yakavets, Ilya Marchal, Sophie Debayle, Manon Pons, Thomas Bezdetnaya, Lina Marchal, Frédéric |
author_facet | Mangeolle, Tristan Yakavets, Ilya Marchal, Sophie Debayle, Manon Pons, Thomas Bezdetnaya, Lina Marchal, Frédéric |
author_sort | Mangeolle, Tristan |
collection | PubMed |
description | Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application. |
format | Online Article Text |
id | pubmed-6116267 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61162672018-08-31 Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis Mangeolle, Tristan Yakavets, Ilya Marchal, Sophie Debayle, Manon Pons, Thomas Bezdetnaya, Lina Marchal, Frédéric Nanomaterials (Basel) Review Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application. MDPI 2018-07-26 /pmc/articles/PMC6116267/ /pubmed/30050022 http://dx.doi.org/10.3390/nano8080572 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mangeolle, Tristan Yakavets, Ilya Marchal, Sophie Debayle, Manon Pons, Thomas Bezdetnaya, Lina Marchal, Frédéric Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis |
title | Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis |
title_full | Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis |
title_fullStr | Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis |
title_full_unstemmed | Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis |
title_short | Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis |
title_sort | fluorescent nanoparticles for the guided surgery of ovarian peritoneal carcinomatosis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116267/ https://www.ncbi.nlm.nih.gov/pubmed/30050022 http://dx.doi.org/10.3390/nano8080572 |
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