Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review

D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, incl...

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Detalles Bibliográficos
Autores principales: Li, Yuying, Han, Hui, Yin, Jie, Li, Tiejun, Yin, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116324/
https://www.ncbi.nlm.nih.gov/pubmed/30175260
http://dx.doi.org/10.1016/j.aninu.2018.04.003
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author Li, Yuying
Han, Hui
Yin, Jie
Li, Tiejun
Yin, Yulong
author_facet Li, Yuying
Han, Hui
Yin, Jie
Li, Tiejun
Yin, Yulong
author_sort Li, Yuying
collection PubMed
description D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, including nutritional potential, regulation on reproduction and hormone biology, and neuron protection. This article mainly reviews the synthesis, racemization, and physiological functions of D-aspartate with emphasis on the potential in diseases.
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spelling pubmed-61163242018-08-31 Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review Li, Yuying Han, Hui Yin, Jie Li, Tiejun Yin, Yulong Anim Nutr Review D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, including nutritional potential, regulation on reproduction and hormone biology, and neuron protection. This article mainly reviews the synthesis, racemization, and physiological functions of D-aspartate with emphasis on the potential in diseases. KeAi Publishing 2018-09 2018-04-16 /pmc/articles/PMC6116324/ /pubmed/30175260 http://dx.doi.org/10.1016/j.aninu.2018.04.003 Text en © 2018 Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Li, Yuying
Han, Hui
Yin, Jie
Li, Tiejun
Yin, Yulong
Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_full Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_fullStr Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_full_unstemmed Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_short Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_sort role of d-aspartate on biosynthesis, racemization, and potential functions: a mini-review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116324/
https://www.ncbi.nlm.nih.gov/pubmed/30175260
http://dx.doi.org/10.1016/j.aninu.2018.04.003
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