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Data on the aquaporin gene expression differences among ρ(0), clinically relevant radioresistant, and the parental cells of human cervical cancer and human tongue squamous cell carcinoma

We present data about mitochondrial DNA (mtDNA) copy number and aquaporin (AQP) gene expression in clinically radioresistant (CRR), ρ(0), and their parental cells from human cervical cancer and human tongue squamous cell carcinoma. In both ρ(0) and CRR cells, the mtDNA copy number was lower than for...

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Detalles Bibliográficos
Autores principales: Takashi, Yuko, Tomita, Kazuo, Kuwahara, Yoshikazu, Nabika, Hideki, Igarashi, Kento, Nagasawa, Taisuke, Kurimasa, Akihiro, Fukumoto, Manabu, Nishitani, Yoshihiro, Sato, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116339/
https://www.ncbi.nlm.nih.gov/pubmed/30175205
http://dx.doi.org/10.1016/j.dib.2018.08.025
Descripción
Sumario:We present data about mitochondrial DNA (mtDNA) copy number and aquaporin (AQP) gene expression in clinically radioresistant (CRR), ρ(0), and their parental cells from human cervical cancer and human tongue squamous cell carcinoma. In both ρ(0) and CRR cells, the mtDNA copy number was lower than for the parental strain. In addition, the obtained data suggest an association between the gene expression levels of AQP (1, 3, 8, and 9) and the difference in hydrogen peroxide (H(2)O(2)) sensitivity between ρ(0) and CRR cells. Here, the composition of cell culture medium differs between CRR and ρ(0) cells. To compare the gene expression of AQPs between ρ(0) and CRR cells, therefore, we showed the data as the ratio to that in their parental cells.