Efficient metabolic evolution of engineered Yarrowia lipolytica for succinic acid production using a glucose-based medium in an in situ fibrous bioreactor under low-pH condition

BACKGROUND: Alkali used for pH control during fermentation and acidification for downstream recovery of succinic acid (SA) are the two largest cost contributors for bio-based SA production. To promote the commercialization process of fermentative SA, the development of industrially important microor...

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Detalles Bibliográficos
Autores principales: Li, Chong, Gao, Shi, Li, Xiaotong, Yang, Xiaofeng, Lin, Carol Sze Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116362/
https://www.ncbi.nlm.nih.gov/pubmed/30181775
http://dx.doi.org/10.1186/s13068-018-1233-6

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