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T-cell costimulation blockade is effective in experimental digestive and lung tissue fibrosis

BACKGROUND: We aimed to investigate the efficacy of abatacept in preclinical mouse models of digestive involvement, pulmonary fibrosis, and related pulmonary hypertension (PH), mimicking internal organ involvement in systemic sclerosis (SSc). METHODS: Abatacept has been evaluated in the chronic graf...

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Detalles Bibliográficos
Autores principales:	Boleto, Gonçalo, Guignabert, Christophe, Pezet, Sonia, Cauvet, Anne, Sadoine, Jérémy, Tu, Ly, Nicco, Carole, Gobeaux, Camille, Batteux, Frédéric, Allanore, Yannick, Avouac, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116494/ https://www.ncbi.nlm.nih.gov/pubmed/30157927 http://dx.doi.org/10.1186/s13075-018-1694-9

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