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ATN-161 as an Integrin α5β1 Antagonist Depresses Ocular Neovascularization by Promoting New Vascular Endothelial Cell Apoptosis

BACKGROUND: ATN-161 (Ac-PHSCN-NH2), an antagonist of integrin α5β1, has shown an important influence in inhibiting tumor angiogenesis and metastasis of other tumor types. However, the mechanism of action of ATN-161 and whether it can inhibit ocular neovascularization (NV) are unclear. This study inv...

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Detalles Bibliográficos
Autores principales:	Sui, Ailing, Zhong, Yisheng, Demetriades, Anna M., Shen, Jikui, Su, Ting, Yao, Yiyun, Gao, Yushuo, Zhu, Yanji, Shen, Xi, Xie, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116638/ https://www.ncbi.nlm.nih.gov/pubmed/30133427 http://dx.doi.org/10.12659/MSM.907446

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