Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach

Inhibition of microtubule function using tubulin targeting agents has received growing attention in the last several decades. The indole scaffold has been recognized as an important scaffold in the design of novel compounds acting as antimitotic agents. Indole-based chalcones, in which one of the ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Preti, Delia, Romagnoli, Romeo, Rondanin, Riccardo, Cacciari, Barbara, Hamel, Ernest, Balzarini, Jan, Liekens, Sandra, Schols, Dominique, Estévez-Sarmiento, Francisco, Quintana, José, Estévez, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116705/
https://www.ncbi.nlm.nih.gov/pubmed/30141353
http://dx.doi.org/10.1080/14756366.2018.1493473

Ejemplares similares

Ejemplares similares