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Spontaneous Proliferation of CD4(+) T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8(+) T Cells

The fast and intense proliferative responses have been well documented for naïve T cells adoptively transferred into chronic lymphopenic hosts. This response known as spontaneous proliferation (SP), unlike antigen-independent lymphopenia-induced proliferation (LIP), is driven in a manner dependent o...

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Detalles Bibliográficos
Autores principales:	Kim, Juhee, Lee, Jun Young, Cho, Kyungjin, Hong, Sung-Wook, Kim, Kwang Soon, Sprent, Jonathan, Im, Sin-Hyeog, Surh, Charles D., Cho, Jae-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116856/ https://www.ncbi.nlm.nih.gov/pubmed/30190718 http://dx.doi.org/10.3389/fimmu.2018.01907

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