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Apigenin alleviates TGF-β1-induced nasal mucosa remodeling by inhibiting MAPK / NF-kB signaling pathways in chronic rhinosinusitis

BACKGROUND: Chronic rhinosinusitis is involved in tissue remodeling of nasal mucosa such as nasal myofibroblast differentiation and extracellular matrix production. Apigenin (4’,5,7-trihydroxyflavone) is a bioflavonoid compound and has anti-tissue remodeling characteristics. The aims of this study w...

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Detalles Bibliográficos
Autores principales:	Yang, Hyun-Woo, Kim, Hwee-Jin, Park, Joo-Hoo, Shin, Jae-Min, Lee, Heung-Man
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116943/ https://www.ncbi.nlm.nih.gov/pubmed/30161164 http://dx.doi.org/10.1371/journal.pone.0201595

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