Cargando…

The Insulator Protein CTCF Is Required for Correct Hox Gene Expression, but Not for Embryonic Development in Drosophila

Insulator binding proteins (IBPs) play an important role in regulating gene expression by binding to specific DNA sites to facilitate appropriate gene regulation. There are several IBPs in Drosophila, each defined by their ability to insulate target gene promoters in transgenic assays from the activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gambetta, Maria Cristina, Furlong, Eileen E. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2018
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116963/ https://www.ncbi.nlm.nih.gov/pubmed/30021792 http://dx.doi.org/10.1534/genetics.118.301350

Ejemplares similares

The insulator protein CTCF regulates Drosophila steroidogenesis
por: Fresán, Ujué, et al.
Publicado: (2015)

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos
por: Rekaik, Hocine, et al.
Publicado: (2023)

CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters
por: Ortabozkoyun, Havva, et al.
Publicado: (2022)

Investigation of the Developmental Requirements of Drosophila HP1 and Insulator Protein Partner, HIPP1
por: Glenn, Steve E., et al.
Publicado: (2018)

Micromanagement of Drosophila Post-Embryonic Development by Hox Genes
por: Buffry, Alexandra D., et al.
Publicado: (2022)

Histone Demethylase Activity of Utx Is Essential for Viability and Regulation of HOX Gene Expression in Drosophila
por: Copur, Ömer, et al.
Publicado: (2018)

Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf
por: Chen, Yuyu, et al.
Publicado: (2023)

In vivo studies of the Drosophila insulator factor CTCF reach a Catch 22
por: Karch, François
Publicado: (2015)

CTCF, BEAF-32, and CP190 are not required for the establishment of TADs in early Drosophila embryos but have locus-specific roles
por: Cavalheiro, Gabriel R., et al.
Publicado: (2023)

Loss of the insulator protein CTCF during nematode evolution
por: Heger, Peter, et al.
Publicado: (2009)

The CTCF insulator protein forms an unusual DNA structure
por: MacPherson, Melissa J, et al.
Publicado: (2010)

Septate Junction Proteins Play Essential Roles in Morphogenesis Throughout Embryonic Development in Drosophila
por: Hall, Sonia, et al.
Publicado: (2016)

The Drosophila melanogaster enzyme glycerol-3-phosphate dehydrogenase 1 is required for oogenesis, embryonic development, and amino acid homeostasis
por: Rai, Madhulika, et al.
Publicado: (2022)

CTCF binding landscape in jawless fish with reference to Hox cluster evolution
por: Kadota, Mitsutaka, et al.
Publicado: (2017)

Dissecting CTCF site function in a tense HoxD locus
por: Bruneau, Benoit G.
Publicado: (2021)

The Drosophila BEAF insulator protein interacts with the polybromo subunit of the PBAP chromatin remodeling complex
por: McKowen, J Keller, et al.
Publicado: (2022)

On the Value of Intra-Motif Dependencies of Human Insulator Protein CTCF
por: Eggeling, Ralf, et al.
Publicado: (2014)

Opbp is a new architectural/insulator protein required for ribosomal gene expression
por: Zolotarev, Nikolay, et al.
Publicado: (2017)

The Variable CTCF Site from Drosophila melanogaster Ubx Gene is Redundant and Has no Insulator Activity
por: Ibragimov, A. N., et al.
Publicado: (2022)

Topological screen identifies hundreds of Cp190- and CTCF-dependent Drosophila chromatin insulator elements
por: Kahn, Tatyana G., et al.
Publicado: (2023)

Acquisition of a Leucine Zipper Motif as a Mechanism of Antimorphy for an Allele of the Drosophila Hox Gene Sex Combs Reduced
por: Sivanantharajah, Lovesha, et al.
Publicado: (2014)

Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains
por: Van Bortle, Kevin, et al.
Publicado: (2012)

The insulator functions of the Drosophila polydactyl C2H2 zinc finger protein CTCF: Necessity versus sufficiency
por: Kyrchanova, Olga, et al.
Publicado: (2020)

Erratum to: The Variable CTCF Site from Drosophila melanogaster Ubx Gene is Redundant and Has no Insulator Activity
por: Ibragimov, A. N., et al.
Publicado: (2023)

The expression of Drosophila melanogaster Hox gene Ultrabithorax is not overtly regulated by the intronic long noncoding RNA lncRNA:PS4 in a wild-type genetic background
por: Hermann, Anita, et al.
Publicado: (2021)

Epigenome editing strategies for the functional annotation of CTCF insulators
por: Tarjan, Daniel R., et al.
Publicado: (2019)

The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions
por: Majumder, Parimal, et al.
Publicado: (2008)

Genome-Wide Analysis of the Binding of the Hox Protein Ultrabithorax and the Hox Cofactor Homothorax in Drosophila
por: Choo, Siew Woh, et al.
Publicado: (2011)

Genome-Wide Tissue-Specific Occupancy of the Hox Protein Ultrabithorax and Hox Cofactor Homothorax in Drosophila
por: Slattery, Matthew, et al.
Publicado: (2011)

Shep RNA-Binding Capacity Is Required for Antagonism of gypsy Chromatin Insulator Activity
por: Chen, Dahong, et al.
Publicado: (2019)

Identification of Genes Required for Apical Protein Trafficking in Drosophila Photoreceptor Cells
por: Laffafian, Azadeh, et al.
Publicado: (2019)

Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary
por: Benner, Leif, et al.
Publicado: (2019)

Transcriptome profile in Drosophila Kc and S2 embryonic cell lines
por: Klonaros, Daniel, et al.
Publicado: (2023)

Hox go omics: insights from Drosophila into Hox gene targets
por: Pavlopoulos, Anastasios, et al.
Publicado: (2007)

Fast sequence evolution of Hox and Hox-derived genes in the genus Drosophila
por: Casillas, Sònia, et al.
Publicado: (2006)

Single-cell visualization of mir-9a and Senseless co-expression during Drosophila melanogaster embryonic and larval peripheral nervous system development
por: Gallicchio, Lorenzo, et al.
Publicado: (2020)

Fragments of the Fab-3 and Fab-4 Boundaries of the Drosophila melanogaster Bithorax Complex That Include CTCF Sites Are not Effective Insulators
por: Kyrchanova, O. V., et al.
Publicado: (2022)

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart
por: Gomez-Velazquez, Melisa, et al.
Publicado: (2017)

Programmed Cell Death 2-Like (Pdcd2l) Is Required for Mouse Embryonic Development
por: Houston, Brendan J., et al.
Publicado: (2020)

The Role of Insulation in Patterning Gene Expression
por: Özdemir, Isa, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rad4er2j33a7nmbr1irgb2stb0