PNPLA3 p.I148M and TM6SF2 p.E167K variants do not predispose to liver injury in cholestatic liver diseases: A prospective analysis of 178 patients with PSC

BACKGROUND: The adiponutrin (PNPLA3) p.I148M and transmembrane 6 superfamily member 2 (TM6SF2) p.E167K variants represent major genetic risk factors for progressive liver injury in nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD) and chronic viral hepatitis. The aim of this st...

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Detalles Bibliográficos
Autores principales: Kruk, Beata, Liebe, Roman, Milkiewicz, Małgorzata, Wunsch, Ewa, Raszeja-Wyszomirska, Joanna, Lammert, Frank, Milkiewicz, Piotr, Krawczyk, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117000/
https://www.ncbi.nlm.nih.gov/pubmed/30161167
http://dx.doi.org/10.1371/journal.pone.0202942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117000/
https://www.ncbi.nlm.nih.gov/pubmed/30161167
http://dx.doi.org/10.1371/journal.pone.0202942

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