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Dissecting the mechanism of action of actinoporins. Role of the N-terminal amphipathic α-helix in membrane binding and pore activity of sticholysins I and II

Actinoporins sticholysin I and sticholysin II (St I, St II) are proposed to lyse model and biomembranes via toroidal pore formation by their N-terminal domain. Based on the hypothesis that peptide fragments can reproduce the structure and function of this domain, the behavior of peptides containing...

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Detalles Bibliográficos
Autores principales:	Carretero, Gustavo P. B., Vicente, Eduardo F., Cilli, Eduardo M., Alvarez, Carlos M., Jenssen, Håvard, Schreier, Shirley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117003/ https://www.ncbi.nlm.nih.gov/pubmed/30161192 http://dx.doi.org/10.1371/journal.pone.0202981

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